AOSept vs Everclean: Which Hydrogen Peroxide Contact Lens System Is Better?

Comparative Analysis of Lens Care Systems
Modern contact lens care systems are designed to provide effective disinfection, deposit removal and long-term ocular surface compatibility.
At Rose Optometry and the New Zealand Eye Research Centre (NZERC), lens care recommendations are guided by clinical safety, material compatibility and patient-specific needs.
Two widely used lens care systems include AOSept and EverClean, both designed for high-level lens hygiene and patient comfort.
AOSept
AOSept is a hydrogen peroxide-based lens care system designed for deep cleaning and disinfection of contact lenses.
It is preservative-free after neutralisation, making it suitable for patients with sensitivity to multipurpose solutions.
Key characteristics include:
- High-level microbial disinfection
- Preservative-free final solution
- Effective protein and lipid removal
- Suitability for soft and rigid lenses
- Reduced risk of solution-related irritation
Clinical considerations:
- Requires strict neutralisation process
- Not suitable for direct ocular contact before neutralisation
- requires dedicated case with catalytic disc
Modern tomography systems allow clinicians to identify subtle posterior corneal changes before advanced visual symptoms develop.
EverClean
EverClean is an alternative peroxide-based cleaning system designed to simplify lens care while maintaining effective disinfection.
It uses a tablet-based activation system to initiate the cleaning and neutralisation process.
Key characteristics include:
- Tablet-activated peroxide system
- Dual-phase cleaning and neutralisation
- Preservative-free after completion
- Effective removal of depositscompatibility with a wide range of lens types
Clinical considerations:
- Simplified user workflow compared to traditional peroxide systems
- Requires adherence to full cleaning cycle
- Suitable for patients seeking reduced manual handling
Comparative Clinical Insights
Both AOSept and EverClean provide preservative-free disinfection after neutralisation, making them appropriate for patients with sensitive eyes or solution intolerance.
AOSept is often preferred in clinical settings where predictable and established peroxide protocols are required, particularly in complex lens fittings and long-term management.
EverClean may be beneficial for patients who prefer a more guided or simplified cleaning process due to its tablet-based system.
The selection between these systems depends on:
- Patient compliance and handling ability
- Lens type and wearing schedule
- Ocular surface healthhistory of solution sensitivity
- Clinician preference and experience
Optimising Lens Care Outcomes
Appropriate lens care plays a critical role in maintaining ocular health, reducing infection risk and ensuring long-term comfort.
Advanced lens materials, including rigid gas permeable and specialty lenses, require tailored care systems to maintain performance and safety.
At Rose Optometry and NZERC, lens care recommendations are integrated into a broader clinical management strategy that includes:
- Regular follow-up assessments
- Corneal health monitoring
- Tear film evaluation
- Personalised lens fitting protocols
Patients are advised to follow clinician guidance strictly and avoid deviation from recommended cleaning systems to ensure optimal outcomes.





